DIAGNOSIS OF LIVER FIBROSIS BY NON-INVASIVE ELASTOMETRY BY PATIENTS WITH DISEASES OF THE HEPATOBILIARY SYSTEM

Krasnova Ludmila Ivanovna, Candidate of medical sciences, assistant, sub-department of infectious diseases, Penza Institute of advanced medical studies, lik72@list.ru

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164 patients with various diseases hepatobiliaris systems, including 105 sick of a chronic hepatitis C which besides usual methods of research (the biochemical analysis of blood, definition of markers HBV and HСV, quantitative definition of DNA HBV and RNA HCV method PCR), defined fibrosis a liver a method indirect elastometryae on device "Fibroskan" with a degree estimation fibrosis on scale METAVIR are analysed. It is shown that almost at 60 % of patients with diseases hepatobiliaris systems it is defined fibrosis a liver, among patients with a stage fibro-sis F3-4 patients with CHС prevail. Direct correlation of degree fibrosis a liver by data elastometryae with duration CHС, activity of enzymes and virus loading is revealed.

Biopsya a liver, indirect elastometryae a liver, a chronic hepatitis C – CHС, a virus of a hepatitis C – HCV, a scale of an estimation of degree fibrosis METAVIR.